Getting around Big Bend can be a complicated affair. National Park Headquarters is over 4 hours drive from the nearest commercial airport, and two hours from the train station in Alpine. Backpackers, hikers, and river runners often need help moving their vehicles and equipment from the beginning of their route to the other end.
Flying commercially will only get you part of the way to Big Bend. However, flying in and renting a car is a convenient and enjoyable way to see Big Bend and the West Texas Mountains.
If you come by public transport, you may want to rent a vehicle.